FLIPI Score Calculator

FLIPI Score Calculator for Hematology. Original FLIPI uses 0-1 low, 2 intermediate and 3-5 high prognostic groups. Age exactly 60, hemoglobin exactly 12, LDH exactly at the upper limit and exactly four nodal areas do not earn their respective points. No individual survival percentage is asserted.

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How this calculator works

Original FLIPI adds five binary predictors: age over 60, stage III/IV, hemoglobin below 12 g/dL, LDH above the laboratory upper limit, and more than four involved nodal areas. Maximum 5; exact age 60 contributes zero.

When to use this calculator

Use for baseline prognostic description in follicular lymphoma with the original FLIPI version clearly identified. It is not FLIPI2 and does not independently indicate a need to start therapy.

Inputs used

Age (completed years)
Ann Arbor stage III or IV
Hemoglobin (g/dL)
LDH (U/L)
Laboratory LDH upper limit (U/L)
Number of involved nodal areas

Clinical interpretation

Original FLIPI uses 0-1 low, 2 intermediate and 3-5 high prognostic groups. Age exactly 60, hemoglobin exactly 12, LDH exactly at the upper limit and exactly four nodal areas do not earn their respective points. No individual survival percentage is asserted.

Worked example

Fictional teaching case. Age (completed years): 61; Ann Arbor stage III or IV: Yes; Hemoglobin (g/dL): 11; LDH (U/L): 200; Laboratory LDH upper limit (U/L): 250; Number of involved nodal areas: 5. Result: 4 points. Original FLIPI high-risk group. Contributions in assessment order: 1 + 1 + 1 + 0 + 1 = 4. This is a risk estimate, not a diagnosis, a personal survival prediction, or an automatic treatment/discharge decision. FLIPI is not FLIPI2 and does not determine whether treatment should start.

Limitations and safety notes

Use in follicular lymphoma with clinician-defined nodal areas and stage. The historical cohort predates modern treatment; fixed historical survival percentages are not displayed. FLIPI2 uses different predictors.

Frequently asked questions

Does age 60 earn the original FLIPI age point?

No. The published division is over 60 versus 60 or younger.

What can change the meaning of this result?

References

Original FLIPI derivation specifies strict age >60 and five variables. https://pubmed.ncbi.nlm.nih.gov/15126323/

Editorial review and citation methodology

Maintained by the Quick Medical Calculator Editorial Team. Content record date: September 9, 2026. A content date is not evidence of independent clinical review. Individual clinical sign-off is not recorded on this page.

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