Mayo Score for UC Calculator

Mayo Score for UC Calculator for Gastroenterology. The historical full-Mayo remission endpoint requires a total at most 2 and no component above 1. A total of 2 with a largest component of 2 does not meet it. Full, partial and modified Mayo assessments are not interchangeable.

For shared guidance on choosing a tool and documenting results, read the clinical calculator workflow.

How this calculator works

Enter the full Mayo total (0-12) and the largest of its four component scores from an authorized assessment. The historical ACT remission endpoint requires total no greater than 2 and every component no greater than 1. No questionnaire text is reproduced.

When to use this calculator

Use only after the named source assessment is complete and documented. This companion interprets entered totals or subtotals; it does not recreate missing source items or authorize a treatment decision.

Inputs used

  • Documented full Mayo total
  • Largest documented component score

Clinical interpretation

The historical full-Mayo remission endpoint requires a total at most 2 and no component above 1. A total of 2 with a largest component of 2 does not meet it. Full, partial and modified Mayo assessments are not interchangeable.

Worked example

Fictional teaching case. Documented full Mayo total: 2; Largest documented component score: 2. Result: 2 points. Does not meet that remission endpoint. Full Mayo remission requires total at most 2 and no component above 1. This is an endpoint interpretation of an already completed assessment, not proof of endoscopic or histologic remission.

Limitations and safety notes

Not partial Mayo, modified Mayo, histologic remission or a treatment algorithm. Completion, instrument version, licensing and administration must be checked at the source; a total alone is insufficient.

Frequently asked questions

Can a full Mayo total of 2 establish the historical remission endpoint?

Only if no component exceeds 1. A total of 2 with one component scoring 2 does not meet that endpoint, which also does not establish histologic remission.

References

  • ACT trial endpoint identity and response definition. https://pubmed.ncbi.nlm.nih.gov/16339095/
  • Historical full-Mayo remission endpoint: total <=2 with no subscore >1. https://www.nejm.org/doi/full/10.1056/NEJMoa050516

Editorial review and citation methodology

Maintained by the Quick Medical Calculator Editorial Team. Content record date: September 9, 2026. A content date is not evidence of independent clinical review. Individual clinical sign-off is not recorded on this page.

  • Prefer original validation studies for scoring systems and prediction tools.
  • Use current specialty society guidance, transplant allocation policy, public health guidance, or regulator resources when they govern clinical use.
  • Include limitations and safety notes when a calculator is population-specific, context-dependent, or unsuitable as a standalone decision tool.

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