Creatinine Clearance Calculator

How this calculator works

Creatinine clearance is commonly estimated with Cockcroft-Gault using age, weight, sex, and serum creatinine.

Inputs used

• Age
• Weight
• Sex
• Serum creatinine

Clinical interpretation

Use estimated creatinine clearance mainly for medication dosing workflows where the drug label or protocol specifies Cockcroft-Gault.

Limitations and safety notes

Estimates are unreliable in rapidly changing renal function, extremes of body size, low muscle mass, pregnancy, and non-steady-state creatinine.

References

• Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976.
• Drug-specific renal dosing guidance and institutional pharmacy protocols.

Editorial review and citation methodology

Reviewed by the Quick Medical Calculator Editorial Team. Last reviewed: June 19, 2026. The review checks calculator inputs, intended population, interpretation, limitations, and source alignment.

• Prefer original validation studies for scoring systems and prediction tools.
• Use current specialty society guidance, transplant allocation policy, public health guidance, or regulator resources when they govern clinical use.
• Include limitations and safety notes when a calculator is population-specific, context-dependent, or unsuitable as a standalone decision tool.