Insulin Sensitivity QUICKI Calculator

Insulin Sensitivity QUICKI Calculator for Endocrinology. Higher QUICKI generally corresponds to greater modeled insulin sensitivity in the studied setting. No universal normal/resistant bands are applied, including no universal 0.339 cutoff. The original derivation established research associations, not an interchangeable diagnostic threshold for every population.

For shared guidance on choosing a tool and documenting results, read the clinical calculator workflow.

How this calculator works

QUICKI = 1 / [log10(fasting insulin) + log10(fasting glucose in mg/dL)]. Glucose entered in SI units is multiplied by 18.0182 before taking the logarithm. The positive-domain implementation rejects an insulin-glucose product at or below 1 rather than displaying infinity or a nonphysiologic negative index.

When to use this calculator

Use as a fasting research or educational sensitivity estimate with specified laboratory methods. It is not a stand-alone diagnostic test or medication-selection rule. Compare like sampling conditions and assays before interpreting changes.

Inputs used

  • Fasting glucose in mmol/L or mg/dL
  • Fasting insulin in micro-units/mL

Clinical interpretation

Higher QUICKI generally corresponds to greater modeled insulin sensitivity in the studied setting. No universal normal/resistant bands are applied, including no universal 0.339 cutoff. The original derivation established research associations, not an interchangeable diagnostic threshold for every population.

Worked example

Glucose 100 mg/dL (100 / 18.0182 mmol/L) and insulin 12 give 1 / log10(1200) = approximately 0.324762. Glucose 10 mg/dL and insulin 0.1 give a product of 1 and a zero denominator; the tool rejects that combination.

Limitations and safety notes

Insulin assay variation, secretion, fasting conditions and treatment can undermine comparison. Positive inputs alone do not ensure a meaningful logarithmic result. Extreme accepted software values are not proof of clinical applicability, and this index is not HOMA2 or a clamp measurement.

Frequently asked questions

Can I take logarithms of mmol/L glucose directly?

No. This convention requires glucose in mg/dL. The tool converts it first; using the wrong numerical units changes the index.

Does a result below 0.339 diagnose resistance?

No universal cutoff follows from this page. Population-specific research findings do not establish a general diagnostic rule.

References

  • Katz et al. 2000 primary QUICKI derivation and fasting research purpose. https://pubmed.ncbi.nlm.nih.gov/10902785/
  • Primary population study and method-specific reference context; no universal 0.339 diagnostic threshold. https://pubmed.ncbi.nlm.nih.gov/11788638/

Editorial review and citation methodology

Maintained by the Quick Medical Calculator Editorial Team. Content record date: September 9, 2026. A content date is not evidence of independent clinical review. Individual clinical sign-off is not recorded on this page.

  • Prefer original validation studies for scoring systems and prediction tools.
  • Use current specialty society guidance, transplant allocation policy, public health guidance, or regulator resources when they govern clinical use.
  • Include limitations and safety notes when a calculator is population-specific, context-dependent, or unsuitable as a standalone decision tool.

Related reviewed calculators